A Review on Substituted Thiadiazole and its Antimicrobial Activity
Keywords:Antimicrobial activity, Thiadiazole
Five-member heterocyclic compound show various type of biological activity among them 2,5-disubstituted 1,3,4-thiadiazole are associated with diverse biological activity probably virtue of –N=C-S grouping. Therapeutic importance of these rings prompted us to developed selective molecules in which substituted could be arrange in a pharmacophoric pattern to display higher pharmacological activity. Thiadiazole have occupied an important place in drug industry.1,3,4-thiadiazole have wide application in many field. Earliest uses were in the pharmaceutical area as an antibacterial with sulphonamide drugs. Some of other uses are antitumor, anti-inflammatory, pesticide, dyes, lubricant and reagent.
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Copyright (c) 2020 Rekha Birle, Nandu Kayande, Nandini Kushwah, Nisha Hirve, Aarti Patidar
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