Formulation and Evaluation of Fexofenadine HCL Oral Dispersable Tablets

Authors

  • Lakshmi Sujatha Kalla Assistant Professor, Department of Pharmaceutics, VJ's College of Pharmacy, Diwancheruvu, India
  • M. Lakshmi Prasanna Associate Professor, Department of Pharmaceutics, VJ's College of Pharmacy, Diwancheruvu, India
  • N. V. V. Jaganmohan Reddy Associate Professor, Department of Pharmaceutics, VJ's College of Pharmacy, Diwancheruvu, India

Keywords:

Solid dispersion, Hydriphillic carrier, FT-IR, Spectroscopy, HP beta cyclodextrine

Abstract

Fexofenadine chloride is an anti-histamine drug used in the treatment of hayfever and allergies symptoms. its oral absorption is 33% and having 14.4 hrs of half-life and belongs to BCS class II drug., a favourable formulation which can enhance solubility and dissolution rate of this model drug may help effectively in the treatment of bacterial infections. Efficiency and bioavailability of poorly soluble drug Fexofenadine HCL through solid dispersion technique using HP Beta cyclodextrine and beta cyclodextrine. the evaluation parameters and method of preparation of physical mixtures and solid dispertions of Fexofenadine HCL by solvent evaporation was explained. Charecterization in solid state was done by various analytical techniques such as FT-IR studies.

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Published

15-07-2020

How to Cite

[1]
L. S. Kalla, M. L. . Prasanna, and N. V. V. . Jaganmohan Reddy, “Formulation and Evaluation of Fexofenadine HCL Oral Dispersable Tablets”, IJRESM, vol. 3, no. 7, pp. 75–81, Jul. 2020.

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